Targeted sleep modulation with auditory stimulation
In this project, we investigate how auditory stimulation during sleep can be used to interact with specific ongoing brain activity patterns. Deep sleep is characterized by highly structured neuronal dynamics, such as slow waves and spindles, which are thought to play important roles in maintaining brain function. Using targeted auditory stimulation, we aim to probe and modulate these endogenous activity patterns in a controlled manner. With this experimental approach we seek to gain fundamental insight into how they are generated, coordinated, and what functional roles they fulfill in the human brain.
The mechanistic knowledge gained in this project provides an important foundation for translational research. By advancing our understanding of sleep-related brain dynamics and how they can be modulated non-invasively, this work informs other projects aimed at developing diagnostic applications or therapeutic interventions for clinical populations such as ( StimuLOOP)
Research group
Prof. Dr. Reto Huber
Dr. Sara Fattinger
Dr. Sven Leach, Netherlands Institute for Neuroscience, Amsterdam, Niederlande
Vanessa Kasties
Institution:
Child Development Center
Universitäts Kinderspital Zürich
Universität Zürich
Funding
- SNSF Grant 320030_179443
- HMZ Flagship grant ≪SleepLoop≫
- Klinisches Forschungsschwerpunkt der Universität Zürich „Sleep & Health“ (2012–2018)
The LOOP Zürich