Research Interest

  1. Attention deficit hyperactivity disorder (ADHD)
    Genotyping analysis of relevant genes for association with attention or/and hyperactivity phenotypes.
    In addition, association study to parameters such as brain imaging changes, environmental factors as well as therapy response (Drug monitoring). Biomarkers discovery study in peripheral samples in order to discover differential diagnosis and therapy response in children and youth. In the basic science, therapeutic effects of methylphenidate (Ritalin) and atomoxetine will be investigated in vitro and in vivo in order to reveal their therapeutic mechanism of action. Animal models, such as Spontaneous hypertensive rats (SHR) will be used for analysis of the link between metabolic syndrome, hypertension and ADHD in particularly learning deficit.

  2. Anxiety disorders
    Genotyping analysis of relevant genes for association with anxiety phenotypes. In addition, association study to parameters such as brain imaging changes, environmental factors as well as therapy response (Drug monitoring). Biomarkers discovery study in peripheral samples in order to discover differential diagnosis and as well as biomarkers discovery for therapy response in children and youth.

  3. Obsessive Compulsive disorders
    Genotyping analysis of relevant genes for association with anxiety phenotypes. In addition, association study to parameters such as brain imaging changes, environmental factors as well as therapy response (Drug monitoring). Biomarkers discovery study in peripheral samples in order to discover differential diagnosis and therapy response in children and youth.

  4. Autism
    We investigate the genetic and environmental factors that may be as risk factors for Autism. Therefore, genotyping analysis of relevant genes for association with anxiety phenotypes are conducted. In addition, association study to pre- and postnatal parameters are analysed. In vitro, mechanisms of action will be studied on neuronal cell culture.

  5. Learning and memory in children and youth
    Genotyping analysis of relevant genes for association with memory and learning deficits phenotypes. Biomarkers discovery study in peripheral samples in order to discover differential early diagnosis.