Publications

Selected Publications

(2019)

Grünblatt E, Werling AM, Roth A, Romanos M, Walitza S (2019) Association study and a systematic meta-analysis of the VNTR polymorphism in the 3’-UTR of dopamine transporter gene and attention-deficit hyperactivity disorder. J Neural Transm. 126(4):517-529. doi: 10.1007/s00702-019-01998-x. (Epub 2019 Mar 28)

Grünblatt E, Nemoda Z, Werling AM, Roth A, Angyal N, Tarnok Z, Thomsen H, Peters T, Hinney A, Hebebrand J, Lesch KP, Romanos M, Walitza S (2019) The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: association study and meta-anaylsis. Am J Med Genet B Neuropsychiatr Genet. 180B: 365-376 (Epub 2018 Nov 25) doi: 10.1002/ajmg.b.32695

Schote AB, Jäger K, Kroll SL, Vonmoos M, Hulka LM, Preller KH, Meyer J, Grünblatt E, Quednow BB (2019) Glucocorticoid receptor gene variants and lower expression of NR3C1 are associated with cocaine use. Addiction Biology. 24: 730-742 (Epub 2018 May 15) DOI: 10.1111/adb.12632

Zai H, Barta C, Cath D, Eapen V, Geller D, Grünblatt E (2019) New insights and perspectives on the genetics of obsessive-compulsive disorder. Psychiatric Genetics. In Press.

Andreazza AC, Laksono I, Fernandes BS, Toben C, Lewczuk P, Riederer P, Kenneday S, Kapogiannis D, Thibaut F, Gerlach M, Falo C, Kim YK, Grünblatt E, Yatham L, Berk M, Baune BT (2019) Guidelines for the standardized collection of blood-based biomarkers in psychiatry: Steps for laboratory validity- a consensus of the biomarkers task force from the WFSBP. The World J. Biol. Psych. 20(5): 340-351. doi: 10.1080/15622975.2019.1574024. (Epub 2019 Mar 25)

(2018)

Re S, Dogan AA, Ben-Shachar D, Berger G, Werling AM, Walitza S, Grünblatt E (2018) Improved generation of induced pluripotent stem cells from hair derived keratinocytes- a tool to study neurodevelopmental disorders as ADHD. Frontiers in Cellular Neuroscience. 12(321): 1-11 doi: 10.3389/fncel.2018.00321

Jagannath V, Gerstenberger M, Walitza S, Franscini M, Heekeren K, Rössler W, Theodoridou A, Grünblatt E (2018) Neuregulin (NRG1) gene expression predicts functional outcomes in individuals at clinical high-risk for psychosis. Psychiatric Res. 266:143-146. doi: 10.1016/j.psychres.2018.05.025.

Grünblatt E, Bartl J, Walitza S (2018) Methylphenidate enhances neuronal differentiation and reduces proliferation concomitant to activation of Wnt signal transduction pathways. Translational Psychiatry. 8:51 DOI: 10.1038/s41398-018-0096-8

Jagannath V, Gerstenberger M, Correll CU, Walitza S, Grünblatt E (2018) A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia. J Neural Transm. 125(1):89-102 (Epub 2017 Sept 1)

Marinova Z, Walitza S, Grünblatt E (2018) Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line. J Neural Transm. 125(1):103-106 (Epub 2017 August 18)

International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS),… Grünblatt E, Walitza S, et al. Knowles JA, Nestadt G (2018) Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis. Mol. Psychiatry. 23(5): 1181-1188 (Epub 2017 August 1) doi: 10.1038/mp.2017.154

Fineberg NA, Demetrovics Z, Stein DJ, Ioannidis K, Potenza MN, Grünblatt E, Brand M, Billeux J, Carmi L, King D, Grant JE, Yücel M, Dell’Osso B, Rumpf HJ, Hall N, Hollander E, Goudriaan A, Menchon J, Zohar J, Burkauskas K, Martinotti G, Van Ameringen M, Corazza O, Pallanti S, COST Action Network and Chamberlain SR (2018) Manifesto for a European Research Network into Problematic Usage of the Internet. Eur. Neuropsychopharmacol. 28(11):1232-1246 (Epub 2018 Oct 2). https://doi.org/10.1016/j.euroneuro.2018.08.004

Sivastav S, Walitza S, Grünblatt E (2018) Emerging role of miRNA in Attention deficit hyperactivity disorder: A systematic review. Atten Defic Hyperact Disord. 10:49-63. (Epub 2017 May 10) Doi:10.1007/s12402-017-0232-y

(2017)

Marinova Z, Maercker A, Grünblatt E, Wojdacz TK, Walitza S (2017) A pilot investigation on DNA methylation modifications associated with complex posttraumatic symptoms in elderly traumatized in childhood. BMC Research Notes. 10(1):752 DOI: 10.1186/s13104-017-3082-y

Jagannath V, Theodoridou A, Gerstenberger M, Franscini M, Heekeren K, Correll CU, Rössler W, Grünblatt E*, Walitza S* (2017) Prediction analysis for transition to schizophrenia in individuals at clinical high-risk for psychosis: The relationship of DAO, DAOA and NRG1 variants with negative symptoms and cognitive deficits. Frontiers in Psychiatry. 8:292 *Equal contribution. DOI: 10.3389/fpsyt.2017.00292

Grünblatt E, Oneda B, Ekici AB, Ball J, Geissler J, Uebe S, Romanos M, Rauch A, Walitza S (2017) High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder. BMC Medical Genomics. 10(1):68. DOI: 10.1186/s12920-017-0299-5

Grünblatt E, Marinova Z, Roth A, Gardini E, Ball J, Geissler J, Wojdacz TK, Romanos M, Walitza S (2018) Combining genetic and epigenetic parameters of the serotonin transporter gene in obsessive-compulsive disorder. J. Psych Res. 96: 209-217. DOI:10.1016/i.jpsychires.2017.10.010

Jagannath V, Brotzakis ZF, Parrinello M, Walitza S, Grünblatt E (2017) Controversial effects of D-amino acid oxidase activator (DAOA)/G72 on D-amino acid oxidase (DAO) activity in human neuronal, astrocyte, and kidney cell lines: The N-methyl D-aspartate (NMDA) receptor hypofunction point of view. Frontiers in Molecular Neuroscience. 10:342.

Noh HJ, Tang R, Flannick J, O’Dushlaine C, Swofford R, Howrigan D, Genereux D, Johnson J, van Grootheest G, Grünblatt E, Andersson E, Djurfeldt D, Patel P, Koltookian M, Hultman C, Pato M, Pato C, Rasmussen S, Jenike M, Hanna G, Stewart E, Knowles J, Ruhrmann S, Grabe H, Wagner M, Rück C, Mathews C, Walitza S, Cath D, Feng G, Karlsson E, Lindblad-Toh K (2017) Integrating evolutionary and regulatory information with multispecies approach implicates genes and pathways in obsessive-compulsive disorder. Nat. Commun. 8 (1): 744. DOI:10.1038/s41467-017-00831-x

Bartl J, Palazzesi F, Parrinello M, Hommer L, Riederer P, Walitza S, Grünblatt E (2017) The impact of methylphenidate and its enantiomers on dopamine synthesis and metabolism in vitro. Progress in Neuro-Psychopharmacology & Biological. Psych. 79: 281-288.

Dolder PC, Grünblatt E, Mueller F, Borgwardt S, Liechti ME (2017) A single dose of LSD does not alter gene expression of the serotonin 2A receptor gene (HTR2A) or early growth response genes (EGR1-3) in healthy subjects. Frontiers in Pharmacology, Neuropharmacology. 8: 423 (doi: 10.3389/fphar.2017.00423)

Jagannath V, Marinova Z, Monoranu CM, Walitza S, Grünblatt E (2017) Expression of D-amino acid oxidase (DAO/DAAO) and D-amino acid oxidase activator (DAOA/G72) during Development and Aging in the Human Post-Mortem Brain. Frontiers in Neuroanatomy. 11:31.

Marinova Z, Walitza S, Grünblatt E (2017) The hallucinogen 2,5-dimethoxy-4-iodoamphetamine hydrochloride activates neurotrophin receptors in a neuronal cell line and promotes neurites extension. J Neural Transm. 124(6): 749-759 (Epub 2017 March 18)

Marinova Z, Maercker A, Küffer A, Robinson MD, Wojdacz TK, Walitza S, Grünblatt E, Burri A (2017) DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma. BMC Medical Genetics. 18: 21; DOI: 10.1186/s12881-017-0370-2.

Havranek MM, Hulka LM, Tasiudi E, Vonmoos M, Mössner R, Seifritz E, Baumgarnter MR, Grünblatt E, Quednow BB (2017) α2A-adrenergic receptor polymorphisms and mRNA expression levels are associated with delay discounting in cocaine users. Addiction Biology. 22(2): 561-569 (Epub 2015 Nov 8) DOI:10.1111/adb.12324.

Riederer P, Ali S, Bajenaru O., Choi MS., Chopp M., Dobrota V., Grünblatt E., Jellinger K., Kamal MA., Kamal W., Korczyn AD., Leszek J., Michel T., Mushtaq G., Meglic B., Natovich R., Pirtosek Z., Rakusa M., Salkovic-Petrisic M., Schmidt R, Schmitt, A., Sridhar GP., Vecsei L., Wojszel ZB., Yaman H., Zhang ZG., Cukierman-Yaffe T (2017) The diabetic brain and cognition. J Neural Transm. 124(11): 1431-1454. (Epub 2017 Aug 1)

Schmitt A, Martins-de-Souza D, Akbarian S, Cassoli JS, Ehrenreich H, Fischer A, Fonteh A, Gattaz WF, Gawlik M, Gerlach M, Grünblatt E, Halene T, Hasan A, Hashimoto K, Kim YK, Kirchner SK, Kornhuber J, Kraus T, Malchow B, Nascimento JM, Rossner M, Schwarz M, Steiner J, Talib L, Thibaut F, Riederer P, Falkai P and members of the WFSBP Task Force on Biological Markers. (2017) Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III- Molecular mechanisms. (Epub 2016 Oct 26) The World J. Biol. Psych. 18(5): 330-356