Latest Publications

Strobel S, Grünblatt E, Heinsen H, Riederer P, Espach T, Meder M, Monoranu CM (2018) Astrocytes- and microglia specific mitochondria DANN deletions levels in sporadic Alzheimer’s disease. J Alzheimer Dis.

Grünblatt E, Nemoda Z, Werling AM, Roth A, Angyal N, Tarnok Z, Thomsen H, Peters T, Hinney A, Hebebrand J, Lesch KP, Romanos M, Walitza S (2018) The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: association study and meta-anaylsis. Am J Med Genet B Neuropsychiatr Genet. In Press.

Re S, Dogan AA, Ben-Shachar D, Berger G, Werling AM, Walitza S, Grünblatt E (2018) Improved generation of induced pluripotent stem cells from hair derived keratinocytes- a tool to study neurodevelopmental disorders as ADHD. Frontiers in Cellular Neuroscience. In Press. doi: 10.3389/fncel.2018.00321

Grünblatt, Edna; Bartl, Jasmin; Walitza, Susanne (2018). Methylphenidate enhances neuronal differentiation and reduces proliferation concomitant to activation of Wnt signal transduction pathways. Translational Psychiatry, 8(1):51.

Sivastav S, Walitza S, Grünblatt E (2018) Emerging role of miRNA in Attention deficit hyperactivity disorder: A systematic review. Atten Defic Hyperact Disord. 10:49-63. (Epub 2017 May 10) Doi:10.1007/s12402-017-0232-y

Re S, Werling AM, Berger G, Walitza S, Grünblatt E (2017) Modelling attention-deficit hyperactivity disorder: From hair follicles to neurons using induced pluripotent stem cells. Leading Opinions Neurologie & Psychiatrie. 5: 31-33.

Jagannath V, Theodoridou A, Gerstenberger M, Franscini M, Heekeren K, Correll CU, Rössler W, Grünblatt E*, Walitza S* (2017) Prediction analysis for transition to schizophrenia in individuals at clinical high-risk for psychosis: The relationship of DAO, DAOA and NRG1 variants with negative symptoms and cognitive deficits. Frontiers in Psychiatry. 8:292 *Equal contribution. DOI: 10.3389/fpsyt.2017.00292

Grünblatt E, Oneda B, Ekici AB, Ball J, Geissler J, Uebe S, Romanos M, Rauch A, Walitza S (2017) High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder. BMC Medical Genomics. 10(1):68. DOI: 10.1186/s12920-017-0299-5

Grünblatt E, Marinova Z, Roth A, Gardini E, Ball J, Geissler J, Wojdacz TK, Romanos M, Walitza S (2018) Combining genetic and epigenetic parameters of the serotonin transporter gene in obsessive-compulsive disorder. J. Psych Res. 96: 209-217. DOI:10.1016/i.jpsychires.2017.10.010

Jagannath V, Brotzakis ZF, Parrinello M, Walitza S, Grünblatt E (2017) Controversial effects of D-amino acid oxidase activator (DAOA)/G72 on D-amino acid oxidase (DAO) activity in human neuronal, astrocyte, and kidney cell lines: The N-methyl D-aspartate (NMDA) receptor hypofunction point of view. Frontiers in Molecular Neuroscience. 10:342.

Marinova Z, Walitza S, Grünblatt E (2017) Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line. J Neural Transm. 125(1):103-106 (Epub 2017 August 18)

Noh HJ, Tang R, Flannick J, O’Dushlaine C, Swofford R, Howrigan D, Genereux D, Johnson J, van Grootheest G, Grünblatt E, Andersson E, Djurfeldt D, Patel P, Koltookian M, Hultman C, Pato M, Pato C, Rasmussen S, Jenike M, Hanna G, Stewart E, Knowles J, Ruhrmann S, Grabe H, Wagner M, Rück C, Mathews C, Walitza S, Cath D, Feng G, Karlsson E, Lindblad-Toh K (2017) Integrating evolutionary and regulatory information with multispecies approach implicates genes and pathways in obsessive-compulsive disorder. Nat. Commun. 8 (1): 744. DOI:10.1038/s41467-017-00831-x

Bartl J, Palazzesi F, Parrinello M, Hommer L, Riederer P, Walitza S, Grünblatt E (2017) The impact of methylphenidate and its enantiomers on dopamine synthesis and metabolism in vitro. Progress in Neuro-Psychopharmacology & Biological. Psych. P79: 281-288.

Dolder PC, Grünblatt E, Mueller F, Borgwardt S, Liechti ME (2017) A single dose of LSD does not alter gene expression of the serotonin 2A receptor gene (HTR2A) or early growth response genes (EGR1-3) in healthy subjects. Frontiers in Pharmacology, Neuropharmacology. 8: 423 (doi: 10.3389/fphar.2017.00423)

International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS),… Grünblatt E, Walitza S, et al. Knowles JA, Nestadt G (2017) Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis. Mol. Psychiatry. In Press (Epub 2017 August 1) doi: 10.1038/mp.2017.154

Marinova Z, Maercker A, Küffer A, Robinson MD, Wojdacz TK, Walitza S, Grünblatt E, Burri A (2017) DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma. BMC Medical Genetics. 18: 21; DOI: 10.1186/s12881-017-0370-2.

Havranek MM, Hulka LM, Tasiudi E, Vonmoos M, Mössner R, Seifritz E, Baumgarnter MR, Grünblatt E, Quednow BB (2017) α2A-adrenergic receptor polymorphisms and mRNA expression levels are associated with delay discounting in cocaine users. Addiction Biology. 22(2): 561-569 (Epub 2015 Nov 8) DOI:10.1111/adb.12324.

Werling AM, Bobrowski E, Taurines R, Gundelfinger R, Romanos M, Grünblatt E*, Walitza S* (2016) CNTNAP2 gene in high functioning autism: No association according to family and meta-analysis approaches. J Neural Transm. 123(3):35363 (Epub 2015 Nov 11). (* Both authors contributed equally)

Grünblatt E, Bartl J, Iuhos DI, Knezovic A, Trulja V, Riederer P, Walitza S, Salkovic-Petrisic M (2015) Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction. J. Mol. Psych. 3(1): 6. DOI:10.1186/s40303-015-0012-6

Havranek MM, Vonmoos M, Müller CP, Büetiger JR, Tasiudi E, Hulk LM, Preller KH, Mössner R, Grünblatt E, Seifritz E, Quednow BB (2015) Serotonin transporter and tryptophan hydroxylase gene variations mediate working memory deficits of cocaine users. Neuropsychopharmacology. 40(13): 2929-37. (Epub 2015 May 27). DOI: 10.1038/npp.2015.146